Publications

Enterovirus Persistence in Cardiac Cells of Patients Suffering From Idiopathic Dilated Cardiomyopathy is Linked to 5′ Terminal Genomic RNA-Deleted Viral Populations With Viral-Encoded Proteinase Activities. Bouin A, Gretteau P-A, Wehbe M, Renois F, N’Guyen Y, Leveque N, Vu MN, Tracy S, Chapman NM, Bruneval P, Fornes P, Semler BL, and Andreoletti L. Circulation. 2019 Feb 13.

Direct and Indirect Effects on Viral Translation and RNA Replication Are Required for AUF1 Restriction of Enterovirus Infections in Human Cells. Ullmer W, Semler BL. MBio. 2018 Sep 4;9(5). [Full text]

Exploitation of nuclear functions by human rhinovirus, a cytoplasmic RNA virus. Flather D, Nguyen JHC, Semler BL, Gershon PD. PLoS Pathog. 2018 Aug 24;14(8):e1007277. [Full Text]

VPg unlinkase/TDP2 in cardiovirus infected cells: Re-localization and proteolytic cleavage. Maciejewski S, Ullmer W, Semler BL. Virology. 2018 Mar;516:139-146.

Functional Consequences of RNA 5′-Terminal Deletions on Coxsackievirus B3 RNA Replication and Ribonucleoprotein Complex Formation. Lévêque N, Garcia M, Bouin A, Nguyen JHC, Tran GP, Andreoletti L, Semler BL. J Virol. 2017 Jul 27;91(16). [Full Text]

Mammalian Polycistronic mRNAs and Disease. Karginov TA, Pastor DPH, Semler BL, Gomez CM. Trends Genet. 2017 Feb;33(2):129-142. [Full Text]

Diverse Strategies Used by Picornaviruses to Escape Host RNA Decay Pathways. Ullmer W, Semler BL.Viruses. 2016 Dec 20;8(12). [Full Text]

Viral Determinants of miR-122-Independent Hepatitis C Virus Replication. Hopcraft SE, Azarm KD, Israelow B, Lévêque N, Schwarz MC, Hsu TH, Chambers MT, Sourisseau M, Semler BL, Evans MJ. mSphere. 2015 Nov 25;1(1). [Full text]

Generation of Recombinant Polioviruses Harboring RNA Affinity Tags in the 5′ and 3′ Noncoding Regions of Genomic RNAs. Flather D, Cathcart AL, Cruz C, Baggs E, Ngo T, Gershon PD, Semler BL. Viruses. 2016 Feb 4;8(2). [Full Text]

Construction of a subgenomic CV-B3 replicon expressing emerald green fluorescent protein to assess viral replication of a cardiotropic enterovirus strain in cultured human cells. Wehbe M, Huguenin A, Leveque N, Semler BL, Hamze M, Andreoletti L, Bouin A. J Virol Methods. 2016 Apr;230:1-8

Divergent Requirement for a DNA Repair Enzyme during Enterovirus Infections. Maciejewski S, Nguyen JH, Gómez-Herreros F, Cortés-Ledesma F, Caldecott KW, Semler BL. MBio. 2015 Dec 29;7(1):e01931-15. [Full Text]

Picornaviruses and nuclear functions: targeting a cellular compartment distinct from the replication site of a positive-strand RNA virus. Flather D, Semler BL. Front Microbiol. 2015 Jun 18;6:594. [Full Text]

A 21st century perspective of poliovirus replication. Lévêque N, Semler BL. PLoS Pathog. 2015 Jun 4;11(6):e1004825. [Full Text]

A novel Bcr-Abl-mTOR-eIF4A axis regulates IRES-mediated translation of LEF-1.  Tsai BP, Jimenez J, Lim S, Fitzgerald KD, Zhang M, Chuah CT, Axelrod H, Wilson L, Ong ST, Semler BL, Waterman ML. Open Biol. 2014 Nov;4(11):140180. [Full text]

Differential restriction patterns of mRNA decay factor AUF1 during picornavirus infections. Cathcart AL, Semler BL. J Gen Virol. 2014 Jul;95(Pt 7):1488-92. [Full Text]

Revelations from a bicistronic calcium channel gene. Du X, Semler BL, Gomez CM. Cell Cycle. 2014;13(6):875-6. [Full Text]

Differential cleavage of IRES trans-acting factors (ITAFs) in cells infected by human rhinovirus. Chase AJ, Semler BL. Virology. 2014 Jan 20;449:35-44. [Full Text]

Inhibition of poliovirus-induced cleavage of cellular protein PCBP2 reduces the levels of viral RNA replication. Chase AJ, Daijogo S, Semler BL. J Virol. 2014 Mar;88(6):3192-201. [Full Text]

Modification of picornavirus genomic RNA using ‘click’ chemistry shows that unlinking of the VPg peptide is dispensable for translation and replication of the incoming viral RNA. Langereis MA, Feng Q, Nelissen FH, Virgen-Slane R, van der Heden van Noort GJ, Maciejewski S, Filippov DV, Semler BL, van Delft FL,van Kuppeveld FJ. Nucleic Acids Res. 2014 Feb;42(4):2473-82. [Full Text]

Cellular mRNA decay protein AUF1 negatively regulates enterovirus and human rhinovirus infections.  Cathcart, A. L., Rozovics, J. M., and Semler, B. L.  J. Virol. 87:10423-10434 (2013). [Full text]

Poliovirus infection induces the co-localization of cellular protein SRp20 with TIA-1, a cytoplasmic stress granule protein. Fitzgerald, K. D., and Semler, B. L.  Virus Res. 176:223-231 (2013). [Full Text]

Viral proteinase requirements for the nucleo-cytoplasmic re-localization of cellular splicing factor SRp20 during picornavirus infections. Fitzgerald, K. D., Chase, A. J., Cathcart, A. L., Tran, G. P., and Semler, B. L. J. Virol. 87:2390-2400 (2013). [Full Text]

MDA5 detects the double- stranded RNA replicative form in picornavirus-infected cells. Feng, Q., Hato, S. V., Langereis, M. A., Zoll, J., Virgen-Slane, R., Peisley, A., Hur, S., Semler, B. L., van Rij, R. P., and van Kuppeveld, F. J. M. Cell Rep. 2:1187-1196 (2012).  [Full Text]

Picornavirus modification of a host mRNA decay protein. Rozovics, J. M., Chase, A. J., Cathcart, A. L., Chou, W., Gershon, P. D., Palusa, S., Wilusz, J., and Semler, B. L. mBio, 3(6):e00431-12 (2012). [Full Text]

An RNA virus hijacks an incognito function of a DNA repair enzyme.  Virgen-Slane, R., Rozovics, J. M., Fitzgerald, K. D., Ngo, T., Chou, W., van der Heden van Noort, G. J., Filippov, D. V., Gershon,P. D., and Semler, B. L.  Proc. Natl. Acad. Sci. USA 109:14634-14639 (2012). [Full Text]

Viral subversion of host functions for picornavirus translation and RNA replication. Chase, A. J., and B. L. Semler. Future Virology 7:179-191 (2012). [Full Text]

SARS coronavirus nsp1 protein induces template-dependent endonucleolytic cleavage of mRNAs: viral mRNAs are resistant to nsp1-induced RNA cleavage. Huang, C., Lokugamage, K. G., Rozovics, J. M., Narayanan, K., Semler, B. L., and Makino, S. PLoS Pathog. 7:e1002433 (2011). [Full Text]

Re-localization of cellular protein SRp20 during poliovirus infection: bridging a viral IRES to the host cell translation apparatus. Fitzgerald, K. D., and Semler, B. L. PLoS Pathog. 7:e1002127 (2011). [Full Text]

Mechanistic intersections between picornavirus translation and RNA replication. Daijogo, S., and Semler, B. L. Adv Virus Res. 80:1-24 (2011)

Engineered picornavirus VPg-RNA substrates: analysis of a tyrosyl-RNA phosphodiesterase activity. Rozovics, J. M., Virgen-Slane, R., and Semler, B. L. PLoS ONE 6:e16559 (2011). [Full Text]

Alphacoronavirus transmissible gastroenteritis virus nsp1 protein suppresses protein translation in mammalian cells and in cell-free HeLa extracts but not in rabbit reticulocyte lysate. Huang, C., Lokugamage, K. G., Rozovics, J. M., Narayanan, K., Semler, B. L., and Makino, S. J. Virol. 85:638-643 (2011). [Full Text]

Stress-inducible alternative translation initiation of human cytomegalovirus latency protein pUL138. Grainger, L., Cicchini, L., Rak, M., Petrucelli, A., Fitzgerald, K. D., Semler, B. L., and Goodrum, F. J. Virol. 84: 9472-9486 (2010). [Full Text]

Mechanistic consequences of hnRNP C binding to both RNA termini of poliovirus negative-strand RNA intermediates. Ertel, K. J., Brunner, J. E., and Semler, B. L. J. Virol. 84:4229-4242 (2010). [Full Text]

Delayed kinetics of poliovirus RNA synthesis in a human cell line with reduced levels of hnRNP C proteins. Brunner, J. E., Ertel, K. J., Rozovics, J. M., and Semler, B. L. Virology 400:240-247 (2010). [Full text]

Bridging IRES elements in mRNAs to the eukaryotic translation apparatus. Fitzgerald, K. D., and Semler, B. L. Biochim. Biophys. Acta 1789:518-528 (2009). [Full text]

Altered interactions between stem-loop IV within the 5′ noncoding region of coxsackievirus RNA and poly(rC) binding protein 2: effects on IRES-mediated translation and viral infectivity. Sean, P., Nguyen, J. H. C., and Semler, B. L. Virology 389:45-58 (2009). [Full Text]

Picornaviridae: molecular biology. Semler, B. L., and Ertel, K. J. pp. 129-140. In: B. Mahy and M. Van Regenmortel, eds. Encyclopedia of Virology, 3rd edition, vol. 4. Elsevier Ltd., Oxford, U.K. (2008)

The linker domain of poly(rC) binding protein 2 is a major determinant in poliovirus cap-independent translation. Sean, P., Nguyen, J. H. C., and Semler, B. L. Virology 378:243-253 (2008). [Full Text]

Coxsackievirus B RNA replication: lessons from poliovirus. Sean, P., and Semler, B. L. Curr. Top. Microbiol. Immunol. 323:89-121 (2008)

IRES-mediated pathways to polysomes: nuclear versus cytoplasmic routes. Semler, B. L., and Waterman, M. L. Trends Microbiol. 16:1-5 (2008)

Cellular protein modification by poliovirus: the two faces of poly(rC)-binding protein. Perera, R., Daijogo, S., Walter, B. L., Nguyen, J. H. C., and Semler, B. L. J. Virol. 81:8919-8932 (2007). [Full text]

 A nucleo-cytoplasmic SR protein functions in viral IRES-mediated translation initiation. Bedard, K. M., Daijogo, S., and Semler, B. L. EMBO J. 26:459-467 (2007) [Full Text]

An Internal ribosome entry site mediates translation of lymphoid enhancer factor-1. Jimenez, J., Jang, G. M., Semler, B. L., and Waterman, M. L. RNA 11:1385-1399 (2005). [Full Text]

Resistance is futile. Semler, B. L. Nat. Genet. 37:665-666 (2005)

Atomic force microscopy analysis of icosahedral virus RNA. Kuznetsov, Y. G., Daijogo, S., Zhou, J., Semler, B. L., and McPherson, A. J. Mol. Biol. 347:41-52 (2005). [Full Text]

Functional interaction of hnRNP C with poliovirus RNA synthesis initiation complexes. Brunner, J. E., Nguyen, J. H. C., Roehl, H. H., Ho, T. V., Swiderek, K. M., and Semler, B. L. J. Virol. 79:3254-3266 (2005). [Full Text]

The exhaustive list can be found here.