by Sohyeon Park | May 17, 2021 | Abstracts
Title: Exploration of tools for studying metastasis of BRCA1-mutated breast tumors Abstract: Mutations in the BRCA1 gene typically give rise to metastatic triple-negative breast cancers with few treatment options. Genetically, these tumors have high intra-tumor and...
by Sohyeon Park | May 11, 2021 | Abstracts
Title: Region-specific differences in human epidermal differentiation at a single-cell level Abstract: Palmoplantar skin, the thickened skin found on the palms of the hands and soles of the feet, is marked by its increased epidermal thickness and specific pattern of...
by Sohyeon Park | Apr 30, 2021 | Abstracts
Title: Scalable and Accurate Invariant Representation Learning for Single-Cell ATAC-Seq Processing and Integration Abstract: Single-cell sequencing assay for transposase-accessible chromatin (scATAC-seq) provides new opportunities to dissect epigenomic heterogeneity...
by Sohyeon Park | Apr 20, 2021 | Abstracts
Title: Simulation Based Inference Design of Experiment for Mechanistic Acyclic Networks (sbiDOE MAN) Abstract: Biological signaling pathways, such as the bone morphogenetic protein (BMP), Wnt, and JAK-STAT, can be modeled as systems of ordinary differential equations...
by Sohyeon Park | Apr 5, 2021 | Abstracts
Title: Structured Prior-Knowledge in Systems Biology Abstract: Research aims in modern computational biology often involve the exploration of multiple, alternative systems-level representations. Often, the scope of such models (or the practicality of exploring...
