Jonathan H. Vo, John Lowengrub Lab

Title: Glioblastoma Recurrence Modeling Abstract: Glioblastoma is the most lethal and prevalent form of cancer to the central nervous system. Its life expectancy is a few years, and in that time the tumor evolves pretty rapidly while modifying its microenvironment in...

Jonathan Rodriguez, John Lowengrub Lab

Title: Mathematical Modeling of Normal and Cancerous Hematopoiesis Abstract: Chronic myeloid leukemia (CML) is a blood cancer in which there is dysregulation of maturing myeloid cells (granulocytes) driven by a chromosomal mutation which creates the fusion gene,...

Dr. Jing Chen, Virginia Tech

Title: Who Is to Thank for the Rhythms of My Tail? – A Mathematical Study of Circadian Rhythmicity in Poly(A) Tail Length Abstract: The circadian rhythm of our body ultimately derives from rhythmic gene expression in individual cells. As the core clock circuit...

Fairlie Reese, Ali Mortazavi Lab

Title: Investigating the role of alternative isoforms in myogenesis   Abstract: Alternative splicing has long been recognized as a source of transcriptomic diversity in eukaryotes and is known to play a role in the regulation of myogenesis, the process by which...