Dr. Jing Chen, Virginia Tech

Title: Who Is to Thank for the Rhythms of My Tail? – A Mathematical Study of Circadian Rhythmicity in Poly(A) Tail Length Abstract: The circadian rhythm of our body ultimately derives from rhythmic gene expression in individual cells. As the core clock circuit...

Fairlie Reese, Ali Mortazavi Lab

Title: Investigating the role of alternative isoforms in myogenesis   Abstract: Alternative splicing has long been recognized as a source of transcriptomic diversity in eukaryotes and is known to play a role in the regulation of myogenesis, the process by which...

Samuel Morabito, Vivek Swarup Lab

Title: Single-cell meta-analysis uncovers shared and distinct gene-regulatory signatures in disorders of the human brain Abstract: In recent years biotechnological and algorithmic advances in single-cell genomics have led to discoveries in the gene-regulatory...

Michelle N. Ngo, Lowengrub Lab & Shahbaba Lab

Title: Biclustering with Conjoined Dirichlet Processes Abstract: Biclustering is a class of techniques that simultaneously clusters the rows and columns of a matrix to sort heterogeneous data into homogeneous blocks. Although many algorithms have been proposed to find...

Alvaro Fletcher, German Enciso Lab

Title: Nonallosteric mechanism for bounded and ultrasensitive chromatin remodeling Abstract: Chromatin remodeling is an important process for regulating a variety of vital biological processes. However, it remains unclear how certain enzymes decompress the chromatin...

Qingda Hu, Elliot Botvinick Lab

Title: Detecting force transmission pathways in 3D fibrin networks Abstract: Cells receive mechanical cues from their surroundings. Of particular interest are 3D fibrous matrices, offering a more physiological microenvironment. The path of force transmission through...