Emmanuel Dollinger, Nie and Atwood Labs

Title: Understanding the systems-level effects of imiquimod in basal cell carcinoma Abstract: Basal cell carcinoma is the most common skin cancer in the United States. BCC is characterized as rarely invasive and typically easy to resect. However, BCC can be quite...

Elisabeth Rebboah, Ali Mortazavi Lab

Title: Towards constructing single-cell gene regulatory networks of skeletal muscle myogenesis Abstract: The regeneration of adult skeletal muscle from injury and disease is carried out through satellite cells, or muscle stem cells. Typically quiescent and resting on...

Kerrigan Blake, Devon Lawson Lab

Title: Microglial response to breast cancer brain metastasis at single-cell resolution Abstract: Breast cancer brain metastasis (BCBM) affects 10-20% of breast cancer patients with a median survival time of less than two years and very few treatment options. An...

Tessa Morris, Anna Grosberg Lab

Title: Quantitative Evaluation of Cardiac Cell Interactions and Responses to Cyclic Strain Abstract: The ventricular myocardium consists of multiple laminar sheets of two-dimensional cardiac tissues, which (by volume) are primarily composed of highly aligned...

Ria Deshpande, Chang Liu Lab

Title: Expanding Cas9 capabilities using synthetic directed evolution Abstract: CRISPR, bacterial acquired immunity, is an important tool for gene editing across many species. SpCas9, the endonuclease used in this process, snips dsDNA 3 bp upstream of a specific...

Sohyeon Park, Jun Allard Lab

Title: ZEBRAFISH AIRINEME TARGET SEARCH AND OPTIMAL CURVATURE Abstract: In addition to diffusive morphogens, cells in developing tissues also communicate via recently discovered cellular protrusions. Examples include airinemes, which mediate long distance signaling...