Co-Director Dr. Thomas Poulos
Chancellor’s Professor Thomas Poulos received his PhD from UCSD in 1972. Dr. Poulos solved the first known structure of a heme enzyme (cytochrome c peroxidase) as a postdoc before shifting his focus to cytochome P450 for which is now most familiar for. Upon joining the faculty of UC Irvine in 1992, he also initiated structural work and inhibitor design on nitric oxide synthase. Today, his research is focused on understanding the structure/function relationship of heme proteins through the application of x-ray crystallography and a host of other experimental techniques. To learn more about Dr. Poulos, click here.
Co-Director Dr. Douglas Tobias
Professor Douglas Tobias received his PhD from Carnegie Melon University in 1991, where he was involved with the development of novel techniques to be used in molecular dynamics (MD) simulations including some of the first constant pressure MD work. Since joining the faculty of UC Irvine in 2005, he has continued his focus on the application of molecular dynamics simulations to a number of fields including ion behavior at the air-water interface, membrane protein dynamics as well as continuing to develop new techniques for studying proteins in sillico. To learn more about Dr. Tobias, click here.