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Gina Lee Lab at UC Irvine

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Molecular Cell paper

As a follow-up to our previous Cell paper, we have discovered a new mTORC1 downstream effector, FAM120A, which orchestrates the interplay between SREBP-dependent transcription and RNA splicing of lipogenic genes, thereby enhancing lipid synthesis in cancer cells. Applause to Sungyun, Yujin, and all co-authors and collaborators!

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