https://ufind.univie.ac.at/en/person.html?id=103581
Thu, April 13, 2023, 9:00-10:00 am PDT via Zoom
Title: Inversion Methods for Strain and Stiffness Reconstruction in Quantitative Optical Coherence Elastography.
Abstract: We consider optical coherence elastography, which is an emerging research field but still lacking precision and reproducibility. Elastography as an imaging modality aims at mapping of the bio-mechanical properties of a given sample. This problem is widely used in Medicine, in particular for the non-invasive identification of malignant formations inside the human skin or tissue biopsies during surgeries. In term of diagnostics accuracy, one is interested in quantitative values mapped on top of the visualization of the sample rather then only qualitative images.
In this talk, we consider inversion methods for strain and stiffness reconstruction in optical coherence elastography. Mathematically, we deal with two inverse problems – a reconstruction of the mechanical displacement and a reconstruction of the Young’s modulus (stiffness) from optical coherence tomography data of a sample which undergoes a static compression. We demonstrate the performance of the proposed inversion methods on twelve silicone elastomer phantoms with inclusions of varying size and stiffness.
This is a joint work with Lisa Krainz (Medical University of Vienna), Simon Hubmer (Johann Radon Institute Linz), Otmar Scherzer (University of Vienna, Johann Radon Institute Linz), Wolfgang Drexler (Medical University of Vienna).