Apple has released Mac OS X 10.8.3 and Security Update 2013-001. Each of these fixes a large number of critical vulnerabilities in Mac OS X and Mac OS X Server, some of which may lead to unexpected application termination or arbitrary code execution. For more information, see http://support.apple.com/kb/HT5672
Mac OS X 10.8.3 update is available for Mac OS X 10.8.x and Mac OS X Server 10.8.x. Security Update 2012-0021 is available for Mac OS X 10.7.5, Mac OS X Server 10.7.5, Mac OS X 10.6.8 and Mac OS X Server 10.6.8.
Software Update will install either Mac OS X 10.8.3 or Security Update 2013-001, whichever is appropriate for your system.