Publications

Torre, D., Fstkchyan, Y.S., Ho, J.S.Y. et al. Nuclear RNA catabolism controls endogenous retroviruses, gene expression asymmetry, and dedifferentiation, Molecular Cell, Volume 83, Issue 23, 2023, Pages 4255-4271.e9, ISSN 1097-2765, https://doi.org/10.1016/j.molcel.2023.10.036.

Zhao, N., Ho, J.S.Y., Meng, F., et al. Generation of host-directed and virus-specific antivirals using targeted protein degradation promoted by small molecules and viral RNA mimics, Cell Host & Microbe, Volume 31, Issue 7, 2023, Pages 1154-1169.e10, ISSN 1931-3128, https://doi.org/10.1016/j.chom.2023.05.030.

Campisi, L., Chizari, S., Ho, J.S.Y. et al. Clonally expanded CD8 T cells characterize amyotrophic lateral sclerosis-4. Nature 606, 945–952 (2022). https://doi.org/10.1038/s41586-022-04844-5.

Campisi, L., Chizari, S., Ho, J.S.Y. et al. Author Correction: Clonally expanded CD8 T cells characterize amyotrophic lateral sclerosis-4. Nature 608, E34 (2022). https://doi.org/10.1038/s41586-022-05184-0.

Ho, J.S.Y., Mok, B.W.Y, Campisi, L. et al. TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation, Cell, Volume 184, Issue 10, 2618-2632.e17, (2021). https://doi.org/10.1016/j.cell.2021.03.051.

Ho, J.S.Y., Zhu, Z. & Marazzi, I. Unconventional viral gene expression mechanisms as therapeutic targets. Nature 593, 362–371 (2021). https://doi.org/10.1038/s41586-021-03511-5.

Vannini, A. & Marazzi, I. A small nucleosome from a weird virus with a fat genome, Molecular Cell, Volume 81, Issue 17, 2021, 3447-3448, ISSN 1097-2765, https://doi.org/10.1016/j.molcel.2021.08.014.

Cross, G., Ho, J.S.Y., Zacharias, W., et al. Emergency drug use in a pandemic: Harsh lessons from COVID-19, Cell, Volume 184, Issue 22, 2021, 5497-5500, ISSN 0092-8674, https://doi.org/10.1016/j.cell.2021.09.025.

Ho, J.S.Y., Angel, M., Ma, Yixuan. et al. Hybrid Gene Origination Creates Human-Virus Chimeric Proteins during Infection, Cell, Volume 181, Issue 7, 2020, Pages 502-1517.e23, ISSN 0092-8674, https://doi.org/10.1016/j.cell.2020.05.035.

Ho J.S.Y., Wing-Yee Mok B, Campisi L, et al. Topoisomerase 1 inhibition therapy protects against SARS-CoV-2-induced inflammation and death in animal models. bioRxiv [Preprint]. 2020 Dec 1:2020.12.01.404483. doi: 10.1101/2020.12.01.404483. Update in: Cell. 2021 Mar 30;: PMID: 33299999; PMCID: PMC7724667.

Natoli, G., Saccani, S., Bosisio, D. et al. Interactions of NF-κB with chromatin: the art of being at the right place at the right time. Nat Immunol 6, 439–445 (2005). https://doi.org/10.1038/ni1196.

Rialdi, A., Hultquist, J., Jimenez-Morales, D., et al. The RNA Exosome Syncs IAV-RNAPII Transcription to Promote Viral Ribogenesis and Infectivity, Cell, Volume 169, Issue 4, Pages 679-692.e14 (2017), ISSN 0092-8674, https://doi.org/10.1016/j.cell.2017.04.021.

Heaton, N.S, Moshkina, N., Fenouil, R., et al. Targeting Viral Proteostasis Limits Influenza Virus, HIV, and Dengue Virus Infection, Immunity, Volume 44, Issue 1, 2016, Pages 46-58, ISSN 1074-7613, https://doi.org/10.1016/j.immuni.2015.12.017.

Rialdi, A. et al. Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation. Science 352, aad7993 (2016). DOI: 10.1126/science.aad7993.

Miller, M., Rialdi, A., Ho, J. et al. Senataxin suppresses the antiviral transcriptional response and controls viral biogenesis. Nat Immunol 16, 485–494 (2015). https://doi.org/10.1038/ni.3132.14.