The Prospects for Retinal Organoids in Treatment of Retinal Diseases.
Asia-Pacific Journal of Ophthalmology (APJO) 2022, 11(4):314-327.
Xue Y, Lin B, Chen JT, Tang WC, Browne AW, Seiler MJ.
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Co-grafts of human embryonic stem cell derived retina organoids and retinal pigment epithelium in immunodeficient retinal degenerate Royal College of Surgeons rats.
Frontiers in Neuroscience, 15:752958 (2021); special issue “Stem Cell-Based Therapy in Retinal Degeneration”
Thomas BB
, Lin B
, Martinez-Camarillo JC, Zhu D, McLelland BT, Nistor G, Keirstead HS, Humayun MS, Seiler MJ.
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Retinal organoids on-a-chip: a micro-milli bioreactor for long-term organoids maintenance
Lab on a Chip. 2021 Jul; 21(17): 3361-3377.
Xue Y, Seiler MJ, Tang WC, Wang JY, Delgado J, McLelland BT, Nistor G, Keirstead HS, Browne AW.
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Development of a protocol for maintaining viability while shipping organoid-derived retinal tissue
Journal of Tissue Engineering and Regenerative Medicine. 2020 Feb; 14(2): 388-394.
Singh RK, Winkler P, Binette F, Glickman RD, Seiler MJ, Peterson-Jones SM, Nasonkin IO.
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Retinal organoid transplants develop photoreceptors and improve visual function in RCS rats with RPE dysfunction
Investigative Ophthalmology & Visual Sciences. 2020 Sep; 61(11): 34.
Lin B, McLelland BT, Aramant RB, Thomas BB, Nistor G, Keirstead HS, Seiler MJ.
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Detailed visual cortical responses generated by retinal sheet transplants in rats with severe retinal degeneration
The Journal of Neuroscience. 2018 Dec; 38(50): 10709 – 10724.
Foik AT, Lean GA, Scholl LR, McLelland BT, Mathur A, Aramant RB, Seiler MJ, Lyon DC.
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A new immunodeficient retinal dystrophic rat model for transplantation studies using human-derived cells
Graefe’s Archive for Clinical and Experimental Ophthalmology. 2018 Nov; 256(11): 2113 – 2125.
Thomas BB, Zhu D, Lin T-C, Kim YC, Seiler MJ, Martinez-Camarillo JC, Lin B, Shad Y, Hinton DR, Humayun MS.
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Sheets of human retinal progenitor transplants improve vision in rats with severe retinal degeneration
Experimental Eye Research. 2018 Sept; 174: 13-28.
Lin B, McLelland BT, Mathur A, Aramant RB, Seiler MJ.
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Transplanted hESC-derived retina organoid sheets differentiate, integrate, and improve visual function in retinal degenerate rats
Investigative Ophthalmology & Visual Sciences. 2018 May; 59(6): 2586-2603.
McLelland BT, Lin B, Mathur A, Aramant RB, Thomas BB, Nistor G, Keirstead HS, Seiler MJ.
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Vision recovery and connectivity by fetal retinal sheet transplantation in an immunodeficient retinal degenerate rat model
Investigative Ophthalmology & Visual Sciences. 2017 Jan; 58(1): 614-630.
Seiler MJ, Lin RE, McLelland, Mathur A, Lin B, Sigman J, De Guzman AT, Kitzes LM, Aramant RB, Thomas BB.
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A new immunodeficient pigmented retinal degenerate rat strain to study transplantation of human cells without immunosuppresion
Graefe’s Archive for Clinical and Experimental Ophthalmology. 2014 July; 252(7): 1079-1092.
Seiler MJ, Aramant RB, Jones MK, Ferguson DL, Bryda EC, Keirstead HS.
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Computational molecular phenotyping of retinal sheet transplants to rats with retinal degeneration
European Journal of Neuroscience. 2012 June; 35(11): 1692-1704.
Seiler MJ, Jones BW, Aramant RB, Yang PB, Keirstead HS, Marc RE.
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Trophic factors GDNF and BDNF improve function of retinal sheet transplants
Experimental Eye Research. 2010 Nov; 91(5): 727-738.
Yang PB, Seiler MJ, Aramant RB, Yan F, Mahoney MJ, Kitzes LM, Keirstead HS.
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Three-dimensional optical coherence tomography imaging of retinal sheet implants in live rats
The Journal of Neuroscience Methods. 2010 May; 188(2): 250-257.
Seiler MJ, Rao B, Aramant RB, Yu L, Wang Q, Kitayama E, Pham S, Yan F, Chen Z, Keirstead HS.
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Visual restoration and transplant connectivity in degenerate rats implanted with retinal progenitor sheets
European Journal of Neuroscience. 2010 Feb; 31(3): 508-520.
Seiler MJ, Aramant RB, Thomas BB, Peng Q, Sadda SR, Keirstead HS.
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Retinal transplants restore visual responses: trans-synaptic tracing from visually responsive sites labels transplant neurons
European Journal of Neuroscience. 2008 July; 28(1): 208-220.
Seiler MJ, Thomas BB, Chen Z, Wu R, Sadda SR, Aramant RB.
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Vision Improvement in Retinal Degeneration Patients by Implantation of Retina Together with Retinal Pigment Epithelium
American Journal of Ophthalmology. 2008 Aug; 142(2): 172-182.
Radtke ND, Aramant RB, Petry HM, Green PT, Pidwell DJ, Seiler MJ.
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BDNF-treated retinal progenitor sheets transplanted to degenerate rats: improved restoration of visual function
Experimental Eye Research. 2008 Jan; 86(1): 92-104.
Seiler MJ, Thomas BB, Chen Z, Arai S, Chadalavada S, Mahoney MJ, Sadda SR, Aramant RB.
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