Congratulations to Mercè Dalmau (Prof. Szu-Wen Wang’s group). She published a paper “pH-Triggered Disassembly in a Caged Protein Complex” in Biomacromolecules in Oct 2009 (vol 10, iss 12, p3199-3206), where MC2 CM-20 TEM was used to reveal the structure and disassembly of the caged protein complex (see figures above). The results are significant progress toward the use of the caged protein complex as a drug delivery vehicle. This paper and related TEM images have been featured recently in “Research Highlights” of Biopolymers (Vol. 93, no. 2, 2010).
This has been her third paper since Dec 2008. Other two papers are “Thermostability and Molecular Encapsulation within an Engineered Caged Protein Scaffold” published in Biotechnology and Bioengineering in Oct 2008 (vol 101, iss 4, p554-664) and “Design of a pH-Dependent Molecular Switch in a Caged Protein Platform” in Nano Letters in Jan 2009 (vol 9, iss 1, p160-166). The former was highlighted in B&B’s “Spotlight” Feature and TEM images were selected as cover photo in December 2008 (see picture below).
It is a great achievement to publish three high quality papers in such a short period of time!
