Announcement:
Professor Rychnovsky has decided to move towards retirement and will no longer be accepting new graduate students or postdocs. Thank you for your many years of guidance and support, Scott!
Group News:
September 6, 2024
Our wonderful undergraduate student Ngoc (Mina) Le is moving on from the lab today. Best of luck with your future work and graduate school applications!
August 1, 2024
Congratulations to Dr. Bryant Lim for successfully defending his thesis! He will be moving on as a postdoctoral researcher at the University of California, Riverside. (Go Highlanders!)
July 19, 2024
Congratulations to Dr. Jessica Pazienza for successfully defending her thesis! Good luck in your future endeavors, and keep in touch!
April 19, 2024
Congratulations to Dr. Jessica Pazienza on their publication of “Formation of Chromophores from cis-Pinonaldehyde Aged in Highly Acidic Conditions,” alongside Dr. Cynthia Wong, Dr. Sergey Nizkorodov, and (of course) Dr. Scott Rychnovsky. Read further on our publications page!
May 22, 2023
Congratulations to Dr. Paul Carlson on successfully defending his PhD. thesis! Dr. Carlson will be moving on to work at Cogent as a senior scientist. Best of luck in your career; you will be missed!
April 27, 2022
Congratulations to Bryant for his recent publication! Bryant has synthesized a range of molecules for the reactivation of mutants of the P53 protein. This work was published as a collaboration with a number of other labs, totaling 22 authors! Read more on our publications page
April 27, 2022
Congratulations to Dr. Charles Dooley on the publication of his work on the total synthesis of (2R)-Hydroxynorneomajucin! His sequence is a great showcase for a number of classic named reactions, including the Tsuji–Trost allylation, Pauson–Khand reaction, Nagata hydrocyanation, Pummerer rearrangement, and Seyferth-Gilbert homologation. You can find a link to this work in the publications section.
April 19, 2022
After the best-attended thesis defense in recent memory, Chuck is now Dr. Charles Dooley! Dr. Dooley will be moving on to work in Amgen’s process chemistry group on the east coast. Congratulations Chuck, you will be missed!
March 10, 2022
Congratulations to Dr. Leah Salituro on successfully defending her thesis! Leah will be moving on to a senior scientist position at Cogent Biosciences. Good luck Leah, we’ll miss you!
January 30, 2022
We’re excited to congratulate Leah and Jess for publishing their total synthesis of Strasseriolides A and B! Read more about these especially potent antimalarial macrolides and how they were synthesized in the publications section.
April 28, 2021
Congratulations Leah and Sadie for publishing their work on photoactivated protein cross-linkers! You’ll find more about their work on the synthesis of these linkers as well as how our collaborators in the Huang group made use of them in the publications section.
March 5, 2021
Congratulations to Paul, Dr. Burns, Emily, and Shilin for publishing their work on Silacycle-Templated Intramolecular Diels-Alder reactions. Go read more about this work in the publications section!
February 3, 2021
We welcome two first-year graduate students to the lab: Emily Shimizu and Jordan Thompson. Welcome to the lab!
July 31, 2020
Congratulations to Chuck and Dr. Burtea, who just published their work on determining the absolute configuration of cyclic amines with the Competing Enantioselective Conversion method! Read more about their work in the publications section.
February 18, 2020
Congratulations to Dr. Sunshine Burns on successfully defending his PhD. thesis! Dr. Burns will be moving on to work at Johnson and Johnson as a senior scientist in medicinal chemsitry.
February 6, 2020
We welcome our three new first-year students: Kha Nguyen, Jessica Pazienza, and Matthew Duong. Welcome to the lab!!
December 10, 2019
Congratulations to Sunshine, Chuck, and Paul on publishing their work on a new crystallographic method! The method employs osmium tetraoxide to form highly crystalline derivative of olefin substrates. You can view their work on our publications page.
September 9, 2019
Congratulations to Burtea and Jacob on publishing their work on the total synthesis of Himeradine A. The synthesis follows the proposed biosynthesis to form 5 bonds and 4 rings in a single step! You can view their work on our publications page.
August 13, 2019
Congratulations to Sunshine on publishing his total synthesis of Illisimonin A in JACS!! The synthesis features a silacycle templated intramolecular Diels–Alder, a semi-pinacol shift to secure a trans-pentalene, and a late stage C-H oxidation. Excellent work.
June 21, 2019
Congratulations to Dr. Alex Burtea for successfully defending his thesis! He will soon start clapping and saying yolo at Pfizer. We will miss you.
May 29, 2019
Congratulations to Dr. Sarah Block for successfully defending her thesis! Sarah will be leaving us to work at CW Analytical. Good luck Sarah!
December 4, 2018
The Rychnovsky group welcomes four new first year students. Welcome to the group Bryant, Nick, Paul, and Sadie!
September 7, 2018
Congratulations to Burtea for “yoloing” the total synthesis of Kujounin A2. You can check out his new paper here.
June 26, 2018
Congratulations to Jacob, Renzo, Greg and Alex Burtea on their new paper on the second-generation synthesis of (+)-Fastigiatine! You can find the paper here.
June 25, 2018
Congratulations to Sunshine on his new paper in Organic Letters! This collaborative publication uses the CEC method to assign the configuration of alcohols derived from the Ir-catalyzed allylation of acetylenic aldehydes. You can read more about this work here.
May 24, 2018
Congrats to Sarah on her new paper in Analytical Chem on MS-cleavable cysteine-reactive chemical cross-linkers!! Check out her work here.
February 9, 2018
Congratulations to Sunshine for his new paper in JOC, using the CEC method to assign absolute configuration of secondary alcohols bearing electron withdrawing groups. Good work!! You can find the paper here.
December 10, 2017
The Rychnovsky group welcomes new graduate students Chuck Dooley and Leah Salituro. Welcome to the group!
August 15, 2017
Congratulations to Sarah for her new paper in the Journal of Biological Chemistry, using her cross-linkers to probe biological responses to oxidative stress. Check it out at here.
August 1, 2017
Congratulations to Alex Burtea for his recent paper in Organic Letters on determining the absolute configuration of cyclic amines. Check this paper out aquí.
May 16, 2017
Congrats to Sunshine on his recent paper in Organic Letters on determining the absolute configuration of beta-chiral primary alcohols. Take a peek.